Gary Cooper

Henry Louis 'Lou' Gehrig

Teresa Wright

Eleanor Twitchell

Babe Ruth

Babe Ruth

Walter Brennan

Sam Blake

Dan Duryea

Hank Hanneman

Elsa Janssen

Christina 'Mom' Gehrig

Ludwig Stössel

Henry 'Pop' Gehrig

Virginia Gilmore

Myra Tinsley

Bill Dickey

Bill Dickey

Ernie Adams

Miller Huggins

Pierre Watkin

Mr. Twitchell

Harry Harvey

Joe McCarthy

Bob Meusel

Robert W. Meusel (as Robert W. Meusel)

Mark Koenig

Mark Koenig

Bill Stern

Bill Stern

Addison Richards

Coach

Hardie Albright

Van Tuyl

Edward Fielding

Clinic Doctor

George Lessey

Mayor of New Rochelle

Edgar Barrier

Hospital Doctor

Douglas Croft

Lou Gehrig as a Boy

Gene Collins

Billy (Age 8)

David Holt

Billy (Age 17)

Veloz

Specialty Dancer (as Veloz and Yolanda)

Yolanda

Specialty Dancer (as Veloz and Yolanda)

Ed Agresti

Barber (uncredited)

Ernie Alexander

Bellhop with Flowers (uncredited)

Hooper Atchley

Lathered Man in Barber Shop (uncredited)

Edwin August

Restaurant Patron (uncredited)

Bettye Avery

Nightclub Singer (uncredited)

Becky Bohanon

Little Girl (uncredited)

Lynton Brent

Photographer in Hospital (uncredited)

Roy Brent

Yankee Ballplayer (uncredited)

Betty Brewer

Little Girl (uncredited)

Don Brodie

Girl Show Barker (uncredited)

Charles Cane

Plumber (uncredited)

Jack Carr

Plumber (uncredited)

Burr Caruth

Village Storekeeper (uncredited)

Eddy Chandler

Motorcycle Cop #2 (uncredited)

Lane Chandler

Mark - Player in Locker Room (uncredited)

Bill Chaney

Newsboy (uncredited)

Jack Chapin

Photographer (uncredited)

Janet Chapman

Tessie (uncredited)

Spencer Charters

Mr. Larsen (uncredited)

Porter Chase

Weight Guesser (uncredited)

Dane Clark

Fraternity Boy (uncredited)

Heinie Conklin

Wallpaper Hanger (uncredited)

Hal Cooke

Man in Cab (uncredited)

Clancy Cooper

Motorcycle Cop #1 (uncredited)

John Daheim

Reporter in Hospital (uncredited)

Eva Dennison

Mrs. Worthington (uncredited)

Lester Dorr

Disappointed Fan #1 (uncredited)

Peter Du Rey

Photographer in Hospital (uncredited)

Lorna Dunn

Clinic Nurse (uncredited)

Jim Farley

Spectator (uncredited)

Frank Faylen

Yankee Third Base Coach (uncredited)

Walter Fenner

Dentist (uncredited)

Pat Flaherty

Yankee Ballplayer (uncredited)

Rosina Galli

Mrs. Fabrini (uncredited)

Vaughan Glaser

Doctor in Gehrig Home (uncredited)

Mary Gordon

Maid (uncredited)

Herschel Graham

Spectator (uncredited)

George Guhl

Second Paper Hanger (uncredited)

Eddie Hall

Reporter in Hospital Room (uncredited)

Harry Hayden

Department Store Manager (uncredited)

Vinton Hayworth

Fraternity Boy (uncredited)

Oscar 'Dutch' Hendrian

Furniture Mover (uncredited)

John Hiestand

Announcer (uncredited)

Earle Hodgins

Bottle Game Operator (uncredited)

Fay Holderness

Spectator (uncredited)

John Ince

Man in Box Seat (uncredited)

Mitchell Ingraham

Barber (uncredited)

Charles Irwin

Carnival Batting Game Operator (uncredited)

Jack Irwin

Photographer in Hospital (uncredited)

Sheldon Jett

Sportsman at Ballgame (uncredited)

Payne B. Johnson

Boy in Ball Park (uncredited)

John Kellogg

Fraternity Boy (uncredited)

Colin Kenny

Yankee Player on Train (uncredited)

Donald Kerr

Photographer (uncredited)

Richard Kipling

Broker (uncredited)

Pat Lane

Wheel of Chance Barker (uncredited)

Larry Lawson

Barker (uncredited)

Rex Lease

Spectator (uncredited)

Theodore Lorch

Neighbor Leaning Through Window (uncredited)

Frank Lyman

Fraternity Boy (uncredited)

Wilbur Mack

Man Outside Yankee Stadium (uncredited)

Dave Manley

Mayor Fiorello LaGuardia (uncredited)

Maurice Marks

Player (uncredited)

Francisco Marán

Rathskeller Headwaiter (uncredited)

John C. McCallum

Minor Role (uncredited)

Ralph McCullough

Reporter in Hospital (uncredited)

George McDonald

Wally Pipp (uncredited)

Matt McHugh

Strength Machine Operator (uncredited)

James McNamara

Rathskeller Manager (uncredited)

Wilmuth Merkyl

Spectator (uncredited)

Howard M. Mitchell

Sportsman at Ballgame (uncredited)

Irving Mitchell

Headwaiter (uncredited)

Pat Moriarity

Policeman in 1915 (uncredited)

Tom Neal

Fraternity Boy (uncredited)

Ray Noble

Orchestra Leader (uncredited)

Patsy O'Byrne

Scrubwoman (uncredited)

George Offerman, Jr.

Freshman (uncredited)

John B. Old

Reporter (uncredited)

Garry Owen

Scorecard Vendor (uncredited)

Sarah Padden

Mrs. Roberts (uncredited)

Emory Parnell

Chicago Policeman O'Doul (uncredited)

Edward Peil Sr.

Policeman (uncredited)

Tom Quinn

Reporter in Hospital (uncredited)

Cyril Ring

Photographer (uncredited)

Henry Roquemore

Disappointed Fan #2 (uncredited)

Art Rowlands

Telephone Man (uncredited)

William Roy

Joe Fabrini (uncredited)

Rip Russell

Laddie (uncredited)

Francis Sayles

Cab Driver (uncredited)

Anita Sharp-Bolster

Sasha's Mother (uncredited)

C. Montague Shaw

Mr. Worthington (uncredited)

Jack Shea

Hammond (uncredited)

John Sheehan

First Paper Hanger (uncredited)

Jack Stewart

Ed Barrow (uncredited)

Brick Sullivan

Policeman (uncredited)

Ben Taggart

Conductor (uncredited)

Walter Tetley

Cake Delivery Boy (uncredited)

Jimmy Valentine

Sasha - Boy Playing Baseball (uncredited)

Gohr Van Vleck

Furniture Mover (uncredited)

Dorothy Vaughan

Eleanor's Landlady (uncredited)

Dorothy Vernon

Family Friend (uncredited)

Malcolm Waite

Big Strength Machine Contestant (uncredited)

James Westerfield

Spectator (uncredited)

Guy Wilkerson

Sportsman at Ballgame (uncredited)

Max Willenz

Mr. Colletti (uncredited)

Buddy Williams

Bootblack (uncredited)

Charles Williams

Little Strength Machine Contestant (uncredited)

Robert Winkler

Murphy (uncredited)

Allen Wood

Freshman (uncredited)

Mike Donovan

Dick Gordon

Radio Listener (uncredited)

Charles Flynn

Fraternity Boy (uncredited)

Jack Gardner

Anthony Walters

Merril (uncredited)